Excenel 50mg/ml sterile powder for injection

Excenel contains ceftiofur which is a beta-lactamase resistant, broad spectrum, bactericidal cephalosporin antibiotic.

The product is indicated for:

• the treatment of cattle with acute respiratory disease in which Pasteurella haemolytica, Pasteurella multocida, Actinobacillus (Haemophilus) somnus or other sensitive bacterial pathogens of the respiratory tract are involved,
• the treatment of cattle with acute interdigital necrobacillosis (foul in the foot) in which Fusobacterium necrophorum and Bacteroides melaninogenicus are involved. As with all antibiotic therapy, treatment of this condition with Excenel should be instituted as early as possible in order to provide maximum clinical effect.
• the treatment of pigs with bacterial respiratory disease in which Actinobacillus (Haemophilus) pleuropneumoniae, Pasteurella multocida and/or Streptococcus suis are involved,
• the treatment of horses with bacterial respiratory disease in which Streptococcus spp. (including Streptococcus zooepidemicus and Streptococcus equi), Staphylococcus spp. and/or Pasteurella spp are involved.

Dosage & Administration

Reconstitution 1 g vial. Reconstitute by adding 20 ml Water for Injection. 4 g vial. Reconstitute by adding 80 ml Water for Injection. For ease of reconstitution use an 18 gauge needle. Rapid addition of diluent will give best results.

Cattle

• 1 mg/kg bodyweight.
• This is equivalent to 1 ml of the reconstituted solution per 50 kg bodyweight.
• For respiratory disease, the dose should be given once daily at 24 hour intervals for 3 to 5 days in total.
• For foul in the foot, the dose should be given once daily at 24 hour intervals for 3 days in total.

Pigs

• 3 mg/kg bodyweight.
• This is equivalent to 1 ml of the reconstituted solution per 16 kg bodyweight.
• The dose should be given once daily at 24 hour intervals for 3 days in total.
• If no response is seen within these periods, the diagnosis should be redetermined.

Horses

• 2 mg/kg bodyweight.
• This is equivalent to 2 ml of the reconstituted solution per 50 kg bodyweight.
• The dose should be given once daily at 24 hour intervals and continued for 48 hours after clinical signs have disappeared.
• A 10 day treatment period is usually adequate.
• A maximum of 10 ml solution should be administered per injection site.
• If no response is seen within 4–5 days, the diagnosis should be redetermined.

Administration

• The intramuscular route only should be used in cattle, pigs and horses.
• In the pig, particular care must be taken to avoid injection into fat tissue.
• Normal aseptic injection techniques should be practiced.

Withdrawals

Cattle: meat: 1 day.

Milk: zero hours.

Pigs: meat: 2 days.

Horses: Not for use in horses intended for human consumption.

Treated horses may never be slaughtered for human consumption.

The horse must have been declared as not intended for human consumption under national horse passport legislation.